LLM Engineer Jobs at Startups

Handshake is seeking a Senior Software Engineer to join the Backend Platform team, with a primary focus on supporting Handshake AI (HAI) and internal AI initiatives. This role involves building and maintaining backend services, shared platform capabilities, and developer tooling. The work will center on core backend platform concerns such as service architecture, APIs, data systems, performance, reliability, and developer experience, with an increasing use of LLMs and agents. The ideal candidate will possess strong backend fundamentals combined with practical knowledge of LLM-powered and agentic systems.

$208k - $260k

Pika

Pika is building the next generation of AI creative tools to make video creation seamless, intuitive, and accessible to everyone. We are seeking a Principal Product Engineer to lead the technical vision, architecture, and roadmap for user-facing systems. In this high-impact role, you will guide the engineering direction for features serving millions of creative users, from intuitive UIs and collaboration tools to real-time interactions and advanced generative AI experiences. You will work closely with product, design, and engineering leadership to deliver robust, scalable, and delightful features, influencing both immediate user experience and long-term product vision from conception to launch and iteration.

Salary not listed

Parallel Wireless is seeking a hands-on technical leader to build and operate a secure local large-language-model (LLM) platform. This platform will enable engineering and business teams to leverage generative AI with proprietary company data, including source code, product documentation, and technical standards, all within a secure, company-controlled environment. This senior individual contributor role involves applied LLM engineering, platform architecture, data pipelines, security, and production operations. You will transform prototypes into a dependable internal capability by selecting and optimizing open-weight models, building permission-aware retrieval systems, creating reusable APIs and tools, integrating with existing workflows, and establishing metrics for quality, safety, latency, capacity, and business value. The role emphasizes building a trustworthy enterprise LLM solution that includes robust source grounding, access controls, repeatable evaluation, observable services, and a sustainable operating model.

Salary not listed

Isomorphic Labs is applying frontier AI to drug discovery to accelerate scientific breakthroughs and develop life-changing medicines. We are building a world-leading drug design engine using predictive and generative AI models. This role is an exciting opportunity to contribute to frontier research at the intersection of AI and drug design, working in a highly creative, iterative environment within the model performance and scaling team. You will partner with scientists and engineers to scale foundational models that will transform the biopharmaceutical world, applying novel techniques to model and systems performance optimizations, as well as machine learning, computational biology, and chemistry problems.

Salary not listed

Parallel Wireless is seeking a driven PHY SW Engineer to join their R&D team. This role will focus on developing advanced, carrier-grade 4G cellular communication solutions, emphasizing performance, reliability, and AI-driven development. The engineer will contribute to building the software behind next-generation cellular networks and shaping the future of telecommunications through innovative and sustainable solutions.

Salary not listed